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Creatine supplementation alone, and mainly in combination with exercise training, may improve glucose metabolism in healthy individuals and insulin-resistant individuals, such as in those with type 2 diabetes mellitus. Creatine itself may stimulate insulin secretion in vitro, improve muscle glycogen stores and ameliorate hyperglycemia in animals. It has been speculated that creatine supplementation combined with exercise training could result in additional improvements in glucose metabolism when compared with each intervention separately. The possible mechanism underlying the effects of combined exercise and creatine supplementation is an enhanced glucose transport into muscle cell by type 4 glucose transporter (GLUT-4) translocation to sarcolemma.

In this talk, Prof. Bruno Gualano PhD (University of Sao Paulo, Brazil) presents about the ""Potential of Creatine in Glucose Management and Diabetes"".

Access the full article for free ⬇️⬇️
Solis, M.Y.; Artioli, G.G.; Gualano, B. Potential of Creatine in Glucose Management and Diabetes. Nutrients 2021, 13, 570. https://doi.org/10.3390/nu13020570



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