🔍 Ever wondered why your Vitamin B12 levels are through the roof even when you're feeling inexplicably low? Dr. J breaks down the perplexing world of high B12 levels and what it means for your health.

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🎥 Intro:
Dr. J addresses the common concern of elevated Vitamin B12 levels in the absence of supplementation or injection.
Encourages viewers to check out previous videos on B12 for a comprehensive understanding.

🧬 Functional Genetics and B12:
Highlights the importance of understanding functional genetic factors affecting B12 absorption, transportation, and metabolism.
Emphasizes the connection between genetic factors and symptoms like fatigue, low libido, memory issues, and more.

📈 High B12 Levels Without Supplementation:
Discusses the scenarios where B12 levels are unexpectedly high, even without external supplementation or injections.
Stresses the need for a washout period to obtain accurate baseline levels.
Raises questions about the bioavailability of B12 at the cellular level.

🔍 Paradoxical High B12 and Symptoms:
Explores the underappreciated phenomenon of high B12 levels coexisting with symptoms typically associated with B12 insufficiency.
Refers to scientific studies discussing poor tissue transportation and utilization of B12 at the cellular level.

🔬 Health Conditions to Rule Out:
Urges viewers to consider serious health conditions like cancers, myeloproliferative diseases, liver, and kidney diseases when B12 levels are unexpectedly high.
Recommends a comprehensive blood panel, including CBC, iron panel, liver enzymes, and kidney function tests.

🧪 Functional Genetic Tests and Biomarkers:
Advocates for functional genetic tests, especially those focusing on SNPs related to B12 metabolism.
Recommends testing methylmalonic acid (MMA) and homocysteine to assess bioavailability and cellular utilization of B12.

📊 Optimal B12 Levels and Bioavailability:
Challenges the notion of the "normal" B12 range and emphasizes the importance of optimal levels for well-being.
Mentions Japan's progressive approach to B12 levels, considering 500pmol/L up to 1300pmol/L.

⚖️ Conclusion:
Dr. J consolidates the information, acknowledging the common misunderstandings surrounding high B12 levels.
Encourages viewers to rule out serious health conditions and consider functional genetic tests for a holistic assessment.
Reminds viewers to check out other videos for in-depth insights into B12 genetics and why the normal range is flawed.
Invites viewers to subscribe for future content on understanding optimal brain and body function.

🚀 Unravel the mystery behind your high B12 levels! Smash that like button, subscribe for more enlightening content, and let's decode the intricate world of health together. Dr. J, signing off.

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