Here's the Problem with Berberine and How I Formulated the Solution for It
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from Muscle Insider

They just didn't do a good job of Berberine. When you look at ultra processed food and the damage it's doing and the fact that we're sedentary and the fact that we're not fasting like we used to, and the fact that we're not hermetically stressed like we used to be. That's why being on these compounds can be so potent.

The problem with Berberine is there's bioavailability issues. You have to take higher doses, you have to take it three times a day. There is GI distress for a large part of the population. So what I looked at with Dihydroberberine is going to the metabolic downstream metabol. In that pathway that in your gut, Berberine is converted to Dihydroberberine.

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