Mohamad Mohty, MD, PhD, Saint-Antoine Hospital, Paris, France, discusses the difficulties in optimizing stem cell donor sources for the treatment of acute myeloid leukemia via transplantation. Specifically, Prof. Mohty discusses the benefit of haploidentical transplantation, especially in light of the challenges COVID-19 is raising. This interview was recorded via an online conference call with The Video Journal of Hematological Oncology (VJHemOnc).