00:00 - Intro
00:32 - Objectives
00:58 - Case
05:36 – Basic features of headache clinical history
06:36 – Fundoscopy
08:16 – Anatomy of pain: The headache network.
12:31 – Differential diagnosis of primary headache
14:15 – S.N.O.O.P. mnemonic
16:13 – IHS diagnostic criteria for migraine
17:45 - Migraine aura
18:25 - Cluster
21:19 – Treatments for primary headaches
30:14 – Differential diagnosis of secondary headache
30:43 – Idiopathic intracranial hypertension
32:37 – Tumor headache
37:53 – Cerebral venous thrombosis
39:01 – Cervical arterial dissection
40:41 – Giant cell (temporal) arteritis
43:07 – Trigeminal neuralgia
44:58– Case wrap-up
46:56 - Summary: Treatment algorithm

This video is intended for medical students to understand the clinical presentation, differential diagnosis and treatment of primary headaches and the wider differential diagnosis of secondary headaches.

Created by:
Igor Rybinnik, MD
Neurology Clerkship Director
Rutgers Robert Wood Johnson Medical School

Produced and narrated by:
Igor Rybinnik MD
Special appreciation to my wife, Jane Shmidt PhD, who is a migraine sufferer, for narrating the patient history.

Content review:
Pengfei Zhang, MD
Headache Neurologist
Assistant Professor
Rutgers Robert Wood Johnson Medical School

Images, video clip and audio adapted from:
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- Pathophysiology of migraine, Springer Healthcare IME, 2020.
- Parameswaran A, et al. J Oral Maxillofac Surg 2018-76,1873-81
- "Let the Real Estate Games Begin." Selling Sunset, season 2, episode 1. Created by Adam DiVello. Netflix, 2019.
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- Mazzucco S, et al. Neurology 2006; 66:E19.
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- Kandel ER, et al. Principles of Neural Science 5th Edition. McGraw Hill, 2012.
- Nucleus Medical Media, Inc.
- Haouimi A, Radiopaedia.org, rID: 72159.
- T Hines, Mayfield Clinic

Disclaimer: Please note that this material was simplified for educational purposes. For patient management, please review your clinical society's guidelines and engage expert consultation where appropriate. Also, the opinions of the presenters do not necessarily reflect those of Rutgers Robert Wood Johnson Medical School, Robert Wood Johnson University Hospital, or Rutgers University as a whole.