TV doctor and columnist Michael Mosley has gone missing in Greece while on holiday, his agent has confirmed.

A search and rescue operation is under way in Symi, one of the Dodecanese Islands, for Mosley, known for his appearances on The One Show and This Morning, along with fronting documentaries.

A local Facebook group said Mosley went for a walk from Saint Nikolas Beach at around 1.30pm Greek time on Wednesday, but had not returned by Thursday morning.

Mosley is also a columnist for the Daily Mail, and has made a number of films about diet and exercise among his documentaries.

Mosley has been given an Emmy nod for BBC science documentary The Human Face, presented by John Cleese and featuring a raft of human faces including Elizabeth Hurley, Pierce Brosnan and David Attenborough.

He also advocated for intermittent fasting through the 5:2 diet and The Fast 800 diet.

Mosley has four children with his wife Clare Bailey Mosley, also a doctor, author and health columnist, who wrote the recipe book Fast 800 Easy.