Glomerulonephritis
Clinical Problem Solvers Clinical Problem Solvers
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 Published On Dec 8, 2020

Part 2 of the glomerulopathy series.

We tackle glomerulonephritis (GN) in this video.

Nephritic syndrome = nephritic sediment + AKI (HTN, edema).

Mimickers of GN are non-inflammatory glomerular diseases that lead to active urinary sediment and include thin-basement membrane disease, Alport syndrome, and anticoagulation-related nephropathy.

GN in which kidney injury progresses rapidly (over days to weeks) is a rapidly progressive GN. Regardless of the tempo, the schema for GN includes 3 buckets based on the immunofluorescence staining pattern. (1) pauci-immune (minimal to eh zeeero staining), (2) Immune complex (granular deposits), and (3) anti-GBM (linear).

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