The lecture introduces "224V: Conversational Virtual Assistants with Deep Learning" at Stanford, focusing on NLP and its potential to revolutionize knowledge work by automating mundane tasks. The course emphasizes building reliable AI systems, teaching students how to use NLP tools and develop cognitive skills in AI. It includes two homework assignments and project-based learning with close supervision. Professor Lam compares this AI revolution to the Industrial Revolution and highlights past student successes in publishing research.