In this video, we delve into groundbreaking research that brings us closer to curing lupus and other autoimmune diseases. The key lies in understanding the role of Treg cells, or regulatory T-cells, which are crucial for maintaining immune balance. In autoimmune diseases like lupus, Treg cells are often deficient or dysfunctional, leading to the immune system attacking the body’s own tissues.
We'll explore how lupus, a systemic autoimmune disease, impacts millions worldwide by causing damage to multiple organs through the misguided actions of T-cells and B-cells. Discover the specific mechanisms through which Tregs suppress the immune response, including the secretion of cytokines like IL-10 and TGFβ, and how they prevent dendritic cells from directing immune attacks on the body’s own proteins.
Most excitingly, learn about the innovative technique developed by scientists in Australia, where they harvest Tregs from lupus patients, modify them with lentiviruses carrying specific genetic material, and reinfuse them into the patients. This process enhances the Tregs' ability to target and suppress the immune cells causing lupus, offering new hope for an effective cure.
Join us as we break down the science behind this revolutionary approach and what it means for the future of lupus treatment. The cure for lupus is closer than you think!