Multi-Omics Data Integration in Human Exposome Studies - Session 3 - - workshop series - coordinated by ISGlobal (https://www.isglobal.org/en/) and the ATHLETE Project (https://athleteproject.eu/)

Title: Strategies for Multivariate Mediation Frameworks in Environmental Epidemiology

This 3rd session is comprised of one presentation by Dr. Vishal Midya from Icahn School of Medicine at Mount Sinai, New York.

Dr. Midya discusses the strategies for multivariate mediation analyses with multiple chemical exposures, particularly aimed at studies in Environmental
Epidemiology. The workshop also delineates currently available tools to model simultaneous exposures to mixtures of chemicals and how to use them in standard mediation analyses framework with multiple mediators. It is also discussed potential methods and explains what each strategy entails, how to interpret the results meaningfully, and the drawbacks of each tool. In the end, Dr. Midya addresses what each method conveys in the context of chemical environmental health studies and the opportunities for future research involving machine learning techniques for precision environmental health. This talk includes multiple examples and illustrates efficient ways to present the results.