Beta sheet is another protein secondary structure, other than alpha helix. Beta sheet forms by joining polypeptide strands together via a hydrogen-bonding network, while the side-chains of amino acids are pointing above or below the sheet.

Just like polypeptide chains, beta sheets are directional as well. The two most common patterns are parallel and anti-parallel. For parallel beta sheets, the N-terminus of one strand is adjacent to the N-terminus of the other stand. For anti parallel beta sheet, the peptide segments run in the opposite direction, in which the N-terminus of one strand is adjacent to the C-terminus of the other strand.

0:00 Secondary structure
0:58 Beta sheet structure
2:38 Parallel vs. anti-parallel beta sheet

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