Learn about the current epidemiology of the 2022 monkeypox outbreak in the United States and Virginia, clinical features of monkeypox disease and assessment of a patient suspected of having monkeypox, infection and control measures in the healthcare setting and at home, diagnostic testing for monkeypox and treatment and management of patients who have monkeypox and the use of vaccination for pre-exposure prophylaxis and post-exposure prophylaxis against monkeypox disease.