Hypothyroidism (When Levothyroxine Doesn't Work)
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 Published On May 27, 2024

Are you taking levothyroxine for hypothyroidism but still not feeling better? In this informative video, we dive deep into the reasons why levothyroxine may not be working effectively, even at high doses.Discover the common culprits behind persistent hypothyroid symptoms, including malabsorption issues caused by medications, supplements, foods, infections like H. pylori, and conditions affecting nutrient absorption. We'll also explore rare cases of tissue resistance to levothyroxine and pituitary or TSH-secreting tumors.Beyond absorption problems, you'll learn about factors that can interfere with thyroid lab tests, such as antibodies against thyroid hormones or heterophilic antibodies, leading to inaccurate results. We'll also discuss the possibility of medication errors or pseudo-malabsorption due to non-compliance.If you've been struggling with hypothyroidism despite taking levothyroxine, this video will provide valuable insights into potential underlying causes and solutions. Don't miss this comprehensive exploration of why levothyroxine sometimes doesn't work as expected, and what steps you can take to get your thyroid health back on track.
.#Hypothyroidism #Levothyroxine #ThyroidTreatment #MalabsorptionIssues #TissueResistance #ThyroidLabTests

For more information, please see the following references:
Thyrotropin-Secreting Pituitary Adenomas
Paolo Beck-Peccoz, MD, Luca Persani, MD, PhD, and Andrea Lania, MD, PhD.
https://www.ncbi.nlm.nih.gov/books/NB...

Update on resistance to thyroid hormone syndromeβ
Hongping Sun1,2, Lin Cao1,2, Rendong Zheng1,2, Shaofeng Xie1,2 and Chao Liu
https://www.ncbi.nlm.nih.gov/books/NB...

Heterophilic antibody interference with TSH measurement on different immunoassay platforms
Xinqi Cheng 1, Xiuzhi Guo 2, Xiaofeng Chai 3, Yingying Hu 2, Xiaolan Lian 3, Guojun Zhang 4
https://pubmed.ncbi.nlm.nih.gov/33285...

How do you approach the problem of TSH elevation in a patient on high-dose thyroid hormone replacement? John C Morris 1
https://pubmed.ncbi.nlm.nih.gov/19226...

Diagnosis and treatment of levothyroxine pseudomalabsorption
D.J. Lips, M.T. van Reisen, V. Voigt, W. Venekamp
https://www.njmonline.nl/getpdf.php?i...

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