Filament changes on the Ender 3 S1 Pro are possible but the method is a little strange.
In this video, I'll quickly show you how you can do it using Cura.
**please note, this works on available firmware at the time of video release and may not work with later versions*

Other Videos Referenced

Creality Slicer Profiles to Cura    • No Profile? No Problem! - Use Crealit...  

Keyring STL https://www.thingiverse.com/thing:334...

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