This video is about an approach to Primary Immunodeficiency Disorders. Primary immunodeficiency disorder is caused by an inherited defect in the immune system that increases the susceptibility to infections. These are of four major types - Antibody or B cell deficiency, Combined T and B cell deficiency, Phagocyte defect and Compliment deficiency. Primary immunodeficiency diseases are unlike secondary or acquired immune deficiency diseases, which are caused by infectious, chemical or radiological agents. AIDS is a prototype of an acquired immune deficiency disease. It has been estimated that there are more than 100 different primary immunodeficiency diseases. All are genetic conditions in which specific cells of the immune system do not function properly. Clinical symptoms range from mild or nonexistent as in the case of selective IgA deficiency to severe symptoms as in the case of severe combined immunodeficiency (SCID). Although the susceptibility to infections is a major consequence of the primary immunodeficiency diseases, they may cause other health problems as well, including allergies, asthma, swollen joints, digestive tract problems, growth problems or an enlarged liver and spleen. Many patients with primary immune deficiency diseases require treatment which may include intravenous gamma globulin infusions, antibiotic therapies, or bone marrow transplantation. In this video I have explained 5 easy steps to diagnose a specific category of Primary Immunodeficiency Disorder.

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